Clinical Trial Screening
Built for Cancer Care Providers and Life Sciences Sponsors
Trial Enrollment
PRISM
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PRISM
Trial Enrollment
Mockup text for our product PRISM Mockup text for our product PRISM
THE PROBLEM
Oncologists and their staff are collectively responsible for matching thousands of patients to hundreds of clinical trials each year. This complex, computationally intensive task is ideally suited for artificial intelligence (AI), yet the methodologies have not changed for decades. Due to the lack of a scalable process for clinicians and their staff to match patients with trials, the task often requires manual chart reviews. Consequently, some patients fall through the cracks and miss out on potentially life-altering treatments.
The Problem
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Oncologists and their staff are collectively responsible for matching thousands of patients to hundreds of clinical trials each year. This complex, computationally intensive task is ideally suited for artificial intelligence (AI), yet the methodologies have not changed for decades.
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Due to the lack of a scalable process for clinicians and their staff to match patients with trials, the task often requires manual chart reviews.
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Consequently, some patients fall through the cracks and miss out on potentially life-altering treatments, while studies take longer to reach their enrollment targets.
The Problem
Oncologists must match thousands of patients to clinical trials annually.
Trial-matching methods remain outdated despite AI’s potential.
Manual chart reviews persist due to a lack of scalable processes.
As a result, some patients miss critical treatment opportunities.
UNDERSTANDING PRISM
Watch our VP of Clinical Data, Regina Schwind, as she introduces Prism, our trial enrollment solution, and explains how we collaborate with various organizations.
How it works
Powered by OncoLLM, Prism can manage various approaches and challenges related to clinical trial enrollment. The platform is designed to help match patients with trials and vice versa, among other capabilities:
1. Patient-to-Trial Matching
Screen patients with upcoming appointments for all locally ongoing trials.
2. Trial-to-Patient Matching
Finds active patients eligible for an upcoming (feasibility) or ongoing trial.
3. Continuous Tracking
Automatically track currently ineligible patients for any future trial opportunities, for example, by automatically detecting disease progression.
We designed our platform to be
01
Proactive
The system continually tracks upcoming or recent appointments and radiology results, and provides an in-basket notification to the clinician and study team when a match is found.
02
Comprehensive
Prism works across your entire portfolio, including federally funded, investigator-initiated, and industry-sponsored trials.
03
Compatible
We integrate with existing EHRs, including Epic, Cerner, OncoEMR and more, and are approved and available on Epic's app marketplace.
04
Scalable
Prism doesn't require complex, study-specific builds, letting you go-live with all your studies on Day 0.
05
Accurate
Our published data shows that our models provide expert level accuracy (NPJ Paper and ASCO Poster)
06
Accessible and Equitable
At-scale prescreening of patients from underserved communities enables research teams to meet their diversity enrollment targets, increasing cancer trial access and equity.
HOW IT WORKS
Powered by OncoLLM, Prism can manage various approaches and challenges related to clinical trial enrollment. The platform is designed to help match patients with trials and vice versa, among other capabilities:
Patient-to-Trial Matching
Screen patients with upcoming appointments for all locally ongoing trials.
Proactive
The system continually tracks upcoming or recent appointments and radiology results, and provides an in-basket notification to the clinician and study team when a match is found.
Compatible
We integrate with existing EHRs, including Epic, Cerner, OncoEMR and several others,and are approved and available on Epic's app marketplace.
Accurate
Our published data shows that our models outperform larger language models and traditional NLP solutions.
Comprehensive
Ability to utilize Prism across your entire portfolio, including federally funded, investigator initiated and sponsor led trials.
Scalable
Prism doesn't require complex, study-specific builds, letting you go-live with all your studies on Day 0
More Accessible and Equitable
At-scale pre-screening of patients from under-served communities enables the research teams to meet their diversity enrolment targets, increasing access and equity in cancer trials.
OUR SOLUTION
We designed our platform to be:
WE DESIGNED OUR PLATFORM TO BE
Proactive
The system continually tracks upcoming or recent appointments and radiology results, and provides an in-basket notification to the clinician and study team when a match is found.
Comprehensive
Prism works across your entire portfolio, including federally funded, investigator-initiated, and industry-sponsored trials.
Compatible
We integrate with existing EHRs, including Epic, Cerner, OncoEMR and more, and are approved and available on Epic's app marketplace.
Scalable
Prism doesn't require complex, study-specific builds, letting you go-live with all your studies on Day 0.
Accurate
Our published data shows that our models outperform larger language models and traditional NLP solutions.
Accessible and Equitable
At-scale prescreening of patients from underserved communities enables research teams to meet their diversity enrollment targets, increasing cancer trial access and equity.
7,000
Patients Screened Monthly
Every patient visit, screened with 100% coverage, driving comprehensive trial matching.
>30%
Increase in Trial Accruals
Boosted enrollment across their clinical trial portfolio in Q3–Q4 2024 vs. 2023.
>70%
Faster Eligibility Screening
Significant reduction in time spent identifying qualified patients.
6 weeks
Rapid Go-Live
Full deployment, including setup of 100 oncology trials that took less than a week.
Our Results
We measured the performance of our platform in accurately identifying trials for patients at a cancer center with hundreds of ongoing oncology trials. Our system achieved an accuracy of over 95% in identifying the correct trial within its top three recommendations, accomplishing this in just minutes. You can learn more about our publication in Nature Digital Medicine at this link.
Life Sciences Sponsors
We’re already partnered with several leading life sciences sponsors to accelerate clinical trials through our platform, live at many of the top cancer centers. Here’s how we can help you:
Accelerate recruitment timelines
Shorten FPI and LPI milestones by reducing screening burden and enabling proactive site-level screening.
Access precise feasibility data
Identify sites and their counts of fully eligible patients, based on real-time EHR-integrated data.
Improve trial design
Uncover which eligibility criteria are overly restrictive and refine protocols accordingly.
Understanding Prism
OUR RESULTS
We measured the performance of our platform in accurately identifying trials for patients at a cancer center with hundreds of ongoing oncology trials. Our system achieved an accuracy of over 95% in identifying the correct trial within its top three recommendations, accomplishing this in just minutes. You can learn more at this link.
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WHY PRISM
Trial sponsors benefit from recruitment of more patients, in less time, from larger and more diverse catchment areas. Plus, our process can be supported by an expert-led team of clinical navigators.
Trial sponsors benefit from recruitment of more patients, in less time, from larger and more diverse catchment areas. Plus, our process can be supported by an expert-led team of clinical navigators.
CONTACT US
888-ONCO-LLM
(888-662-6556)
1 World Trade Center, Ste. 46C
New York, NY 10007